Study of Normal Intestinal Development and Disease in Premature and Term Neonates

Launched by BOSTON CHILDREN'S HOSPITAL · Nov 7, 2024

Keywords

ClinConnect Summary

This clinical trial is focused on understanding how the intestines develop in newborns and young children, especially those who are premature or have intestinal diseases like necrotizing enterocolitis (NEC). Researchers believe that studying human intestines directly, rather than relying on mouse models, will provide better insights into how these organs grow and function. They hope to learn more about critical aspects of intestinal health and the impact of diseases that can affect newborns.

To participate in this study, eligible infants and neonates up to 2 years old must be undergoing intestinal surgery or have had biopsies taken during specific procedures like an endoscopy or colonoscopy. Unfortunately, children older than 2 years or infants not having these specific medical procedures will not qualify. Participants can expect to contribute to important research that could help improve the understanding of intestinal development and diseases, ultimately benefiting future patients. This study is currently preparing to start and is not yet recruiting participants.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Any neonate or infant through 2 years of age having intestinal surgery or intestinal biopsies from an esophogastroduodenoscopy (EGD) or colonoscopy.
• Exclusion Criteria:
• • Children \> 2 years of age.
• • Infants 0-2 years old not undergoing GI surgery or intestinal scope with biopsy procedure.