Feasibility Study of CBCT for IGRT in Cancer Patients

Launched by VARIAN, A SIEMENS HEALTHINEERS COMPANY · Nov 6, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new imaging technology called HyperSight to see if it can improve the quality of images used during radiation therapy for various types of cancer, including head and neck, breast, liver, and gastrointestinal cancers. The goal is to determine if these new images can not only help position patients for their treatments but also assist in planning the radiation therapy itself. By comparing the HyperSight images to traditional images, researchers hope to make radiation therapy more effective for patients.

To participate in this study, you need to be at least 18 years old and currently receiving radiation therapy for one of the specified types of cancer. It's important that a certain type of imaging is already part of your treatment plan. However, if you have serious health issues, are unable to consent, or are part of a vulnerable population, you may not be eligible. Participants can expect to have images taken using the new HyperSight technology, which will be analyzed to see how well they perform compared to standard images. This study is currently recruiting patients, and everyone’s contributions could help improve cancer treatment in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patient age ≥ 18
• • 2. Patient is receiving radiation therapy for head and neck, thorax, liver, breast, genitourinary, or gastrointestinal malignancies
• • 3. A CBCT acquisition for localization is standard of care for the radiation therapy treatment plan being delivered
• Exclusion Criteria:
• • 1. Patient has ECOG Performance Status ≥3.
• • 2. Patient is wheelchair bound.
• • 3. Patient has a life expectancy \<3 months.
• • 4. Patient is unwilling or unable to provide informed consent to participate in the study.
• • 5. Patient is pregnant or has plans for pregnancy during the period of treatment.
• • 6. Patient is part of a vulnerable population (per ISO 14155:2020, "individuals who are unable to fully understand all aspects of the investigation that are relevant to the decision to participate, or who could be manipulated or unduly influenced as a result of a compromised position, expectation of benefits or fear of retaliatory response"). This includes prisoners.