Nutritional Status and Therapy in DMD Patients

Launched by ANKARA UNIVERSITY · Nov 8, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how a special diet can help improve the health and abilities of young boys with Duchenne Muscular Dystrophy (DMD), a condition that affects muscle strength. The study will involve boys aged 4 to 8 years living in Ankara, Turkey. Researchers want to find out if a personalized diet can make a difference in how well these boys are growing and moving around. They will assess each child's nutritional status and provide dietary counseling to help improve their energy, protein, calcium, and fluid intake, especially since many of these boys are also taking corticosteroids, which can have side effects.

To participate in the study, boys must be diagnosed with DMD, able to walk on their own, and currently receiving corticosteroid treatment. Unfortunately, those who cannot walk, have serious health issues, or have certain swallowing or breathing difficulties won't be able to join. Participants can expect to receive detailed nutritional assessments and tailored support throughout the study, which aims to not only improve their nutrition but also to see if this helps with their overall movement and quality of life. The trial is not yet recruiting participants, but it holds promise for helping boys with DMD lead healthier lives.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Clinical diagnosis of Duchenne Muscular Dystrophy (DMD) Must be between 4 and 8 years old Able to ambulate independently Must be residing in Ankara province, Turkey Must be willing to participate and adhere to the dietary intervention, as confirmed by both the patient and their legal guardian(s) Must be currently receiving corticosteroid therapy
• Exclusion Criteria:
• • Inability to read and write in Turkish Wheelchair-bound or unable to ambulate independently Significant liver or kidney dysfunction Scheduled for major surgery within 6 months of study enrollment Symptoms of dysphagia and swallowing difficulties Significant respiratory distress or respiratory insufficiency requiring mechanical ventilation.