Effect of Timing of Dexamethasone During Induction on Postoperative Outcomes
Launched by AABDI MOHAMMED · Nov 10, 2024
Trial Information
Current as of July 01, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how the timing of a medication called dexamethasone affects recovery after surgery. Dexamethasone is often used to help prevent nausea and reduce inflammation. In this trial, some patients will receive dexamethasone before certain anesthetic drugs, some will get it after, and a third group will not receive it at all. The goal is to find out if the timing of the medication can lead to better outcomes, such as less nausea, less pain, and a quicker recovery.
To be eligible for this study, participants must be adults aged 18 or older who are scheduled for certain types of surgeries that last at least 90 minutes. They should be able to give consent and meet specific health criteria, such as being able to safely receive dexamethasone. However, individuals with certain health conditions, allergies, or those who are pregnant or breastfeeding cannot participate. If you join the study, you won’t know which group you’re in, and neither will the doctors treating you, which helps ensure fair results.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Adults aged 18 years or older
- • Scheduled for elective non cardiac surgery requiring general anesthesia
- • surgery last at least 90 minutes
- • scare of more than 5 cm Able to provide informed consent Eligible for dexamethasone administration as part of routine perioperative care
- Exclusion Criteria:
- • Known allergy or hypersensitivity to dexamethasone or related corticosteroids
- • History of uncontrolled diabetes mellitus or significant blood glucose management issues, as dexamethasone may affect glucose levels
- • Severe cardiovascular instability or hemodynamic issues contraindicating study participation
- • Patients receiving immunosuppressive therapy or with conditions affecting the immune system, as corticosteroids may alter immune responses
- • Pregnancy or breastfeeding, due to potential risks to the fetus or infant
- • Current or recent (within 30 days) use of other glucocorticoids, which may interfere with study outcomes
- • Patients with psychiatric or cognitive conditions that impair their ability to consent or adhere to study protocols
- • Lack of informed consent
About Aabdi Mohammed
Aabdi Mohammed is a dedicated clinical trial sponsor committed to advancing medical research through innovative and rigorous study designs. With a focus on improving patient outcomes, Aabdi oversees a diverse portfolio of clinical trials across multiple therapeutic areas. The organization emphasizes collaboration with healthcare professionals and research institutions to ensure the highest standards of ethical conduct and scientific integrity. By prioritizing patient safety and data quality, Aabdi Mohammed aims to contribute valuable insights that drive the development of effective therapies and enhance healthcare practices globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported