Physical Rehabilitation of Older Persons Following a Community-Acquired Infection Hospitalization: a Feasibility Study
Launched by NORDSJAELLANDS HOSPITAL · Nov 12, 2024
Trial Information
Current as of August 25, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is looking into a new way to help older adults recover after being hospitalized for community-acquired infections like pneumonia or urinary tract infections. The focus is on testing a personalized exercise program that starts while patients are still in the hospital and continues for three months after they go home. This program includes video-guided exercises that patients can do at home. The goal is to see if this approach can improve their physical and mental health compared to standard care, which typically does not include such rehabilitation.
To participate in the trial, individuals need to be at least 65 years old or younger if they have a chronic illness, and they must have symptoms of a lower respiratory tract infection or a urinary tract infection. Participants should be able to live independently before their hospital stay and must agree to take part by signing a consent form. The trial aims to assess not only how safe and effective the exercise program is but also how patients feel about it and how it impacts their daily lives. If you or a loved one fit the eligibility criteria, this could be an exciting opportunity to receive support in recovery after an infection.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients aged ≥65 years or ≤65 years if the presence of at least one chronic disease (e.g., diabetes, COPD, heart failure, etc.)
- • Suspicious of a lower respiratory tract infection AND
- • Presence of one or more symptoms of a lower respiratory tract infection such as fever ≥38.3°C, hypothermia \<35.0°C, new onset of cough, pleuritic chest pain, dyspnea, or altered breath sounds on auscultation.
- • Positive urine nitrate test and/or leukocyturia as depicted by positive esterase test or microscopy AND
- • Presence of one or more symptoms of urinary tract infection such as dysuria, urgent or frequent urination, perineal or suprapubic pain, costo-vertebral tenderness or flank pain, fever (ear or rectal temperature of ≥38.2°C or axillary temperature of ≥38.0°C), or history of feeling feverish with shivering or rigors in the past 24 hours.
- • Functionally independent before hospitalization and expected to be discharged to their own homes.
- • Signed informed consent.
- Exclusion Criteria:
- • Hospitalization within the past 14 days.
- • Inability to participate in the study due to dementia, paralysis, or other disorders.
- • Severe aortic valve stenosis or terminal illness.
- • Unstable cardiac arrhythmic disease.
- • High risk for non-adherence as determined by screening evaluation.
- • Already participating in regular exercise training.
- • Unable to understand Danish.
- • Unwilling or unable to give informed consent.
About Nordsjaellands Hospital
Nordsjællands Hospital is a prominent healthcare institution in Denmark, dedicated to advancing medical research and improving patient care through innovative clinical trials. As a part of the North Denmark Region, the hospital is committed to fostering collaboration among healthcare professionals, researchers, and academic institutions to enhance the understanding of various health conditions. With a focus on evidence-based practices, Nordsjællands Hospital aims to drive progress in medical science while ensuring the highest standards of patient safety and ethical compliance in all its clinical research endeavors.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Hillerød, , Denmark
Hvidovre, , Denmark
Hvidovre, , Denmark
Patients applied
Trial Officials
Birgitte Lindegaard, MD, PhD
Principal Investigator
Department of Pulmonary and Infectious Diseases, Copenhagen University Hospital - North Zealand
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported