DEPRECAP: Lung Cancer Screening Programme by LDCT for Patients With COPD or Emphysema.

Launched by INSTITUTO DE INVESTIGACIÓN SANITARIA DE LA FUNDACIÓN JIMÉNEZ DÍAZ · Nov 13, 2024

Keywords

ClinConnect Summary

The DEPRECAP study is looking at how effective lung cancer screening is for patients with chronic obstructive pulmonary disease (COPD) or emphysema. This research is taking place at hospitals in Madrid, Spain, and aims to understand if screening these high-risk patients can help detect lung cancer earlier, potentially reducing the number of deaths caused by late-stage lung cancer. The study also focuses on collecting important health information and samples from participants to support future research on lung cancer and other diseases related to smoking.

To be eligible for this study, participants need to be current or former smokers with a significant history of smoking (at least 30 pack-years) and must have a diagnosis of COPD or emphysema. Those who have had recent cancer (except for certain types of skin cancer) or significant other health issues are not included. If you join the study, you will undergo lung cancer screening using low-dose CT scans, and your health will be monitored over time to see how effective this screening is. This trial is currently recruiting participants, so it's a great opportunity to contribute to important research that could benefit many people in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Current or former smokers (\>15 years of abstinence) with a cumulative smoking exposure of \> 30 pack-years
• • Diagnosis of COPD according to the GOLD guidelines and/or emphysema identified by LDCT and/or a carbon monoxide diffusing capacity (DLCO) lower than 80% of predicted (as per the Global Lung Function Initiative (GLI) equations)
• Exclusion Criteria:
• • Individuals with a recent history of cancer (except non-melanoma skin cancer or carcinoma in situ) as well as those with other medical conditions that posed a significant risk of death were excluded from the study.