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Search / Trial NCT06692400

The Effects of Endotracheal Suctioning on Pain and Serum Markers

Launched by LOMA LINDA UNIVERSITY · Nov 14, 2024

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying how a common procedure called endotracheal tube (ETT) suctioning affects pain and stress levels in adult patients who are in the Intensive Care Unit (ICU) and on ventilators. ETT suctioning is done to clear airways, but it may cause discomfort or pain. The researchers want to find out if this procedure raises pain levels and if it increases certain markers in the blood that show how the body is responding to stress and lack of oxygen.

To participate in the study, individuals need to be at least 18 years old, currently diagnosed with conditions like flu, pneumonia, COVID, or sepsis, and be intubated on a ventilator. Participants will have their pain levels checked before and after the suctioning, and blood samples will be taken at specific times to measure stress markers. This research aims to improve pain management for ICU patients who cannot communicate their discomfort, potentially leading to better care in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adults (aged 18 years and older)
  • Current diagnosis of flu, pneumonia, COVID, or sepsis
  • Intubated and receiving mechanical ventilation.
  • Have arterial lines placed
  • Require endotracheal suctioning as part of their care
  • Exclusion Criteria:
  • Patients receiving neuromuscular blocking agents
  • Contraindications for blood draws (hemoglobin levels below 8.0 g/dL; Jehovah's Witness)

About Loma Linda University

Loma Linda University is a prominent academic institution dedicated to advancing health and wellness through innovative research and education. As a sponsor of clinical trials, Loma Linda University leverages its extensive medical and scientific expertise to conduct rigorous studies aimed at improving patient outcomes and public health. With a commitment to ethical practices and patient safety, the university collaborates with a diverse network of healthcare professionals and researchers to explore novel therapeutic interventions and enhance clinical knowledge across various medical disciplines. Through its clinical trials, Loma Linda University seeks to contribute valuable insights to the medical community and foster advancements in healthcare delivery.

Locations

Loma Linda, California, United States

Patients applied

0 patients applied

Trial Officials

Elizabeth Johnston Taylor, PhD, FAAN

Principal Investigator

Loma Linda University School of Nursing

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported