Clinical Prediction Model for In-Hospital Rebleeding in Acute Non-Variceal Upper Gastrointestinal Bleeding
Launched by JUNWEI YAN · Nov 19, 2024
Trial Information
Current as of August 21, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a new way to predict the risk of rebleeding in patients who have experienced acute non-variceal upper gastrointestinal bleeding, a serious condition that can cause symptoms like vomiting blood or passing black stools. Although current tools help doctors assess recovery, they are not very effective in spotting patients at high risk of rebleeding. The goal of this study is to develop a more accurate prediction model that combines patient symptoms, lab results, and imaging findings, which could help doctors make better decisions about monitoring and treatment, ultimately improving patient outcomes and reducing complications.
To participate in this trial, individuals must be over 18 years old and have been diagnosed with acute non-variceal upper gastrointestinal bleeding, confirmed by an endoscopy within 24 hours of being admitted to the hospital. Patients who have bleeding from other causes or have incomplete medical information will not be eligible. Those who join the study will help researchers gather important data that can lead to a more reliable way for doctors to identify patients at risk for rebleeding, enhancing care in real-world settings.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • age exceeding 18 years,
- • Clinical diagnosis of Acute Non-Variceal Upper Gastrointestinal Bleeding ,
- • patients who underwent endoscopy within 24 hours of admission with confirmation of non-variceal bleeding
- Exclusion Criteria:
- • Upper Gastrointestinal Bleeding during hospitalization;
- • transfer from other hospitals;
- • variceal bleeding;
- • lower gastrointestinal bleeding.;
- • bleeding attributed to systemic diseases like disseminated intravascular coagulation (DIC) and hematological disorders;
- • patients with incomplete clinical data or laboratory test results;
- • patients who either requested early discharge or declined gastroscopy.
About Junwei Yan
Junwei Yan is a dedicated clinical trial sponsor committed to advancing medical research and innovation. With a focus on developing novel therapeutic solutions, Junwei Yan collaborates with leading research institutions and healthcare professionals to design and conduct rigorous clinical studies. The organization emphasizes patient safety, ethical standards, and data integrity, aiming to contribute valuable insights that enhance healthcare outcomes. Through a strategic approach and a commitment to scientific excellence, Junwei Yan is poised to make significant contributions to the field of medicine.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Wuhan, Hubei, China
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported