Sweet Thresholds in Healthy Volunteers Study

Launched by RANVIER HEALTH LTD · Nov 18, 2024

Keywords

ClinConnect Summary

The "Sweet Thresholds in Healthy Volunteers Study" is a research trial that aims to understand how much sugar (sucrose) needs to be mixed with water for healthy people to taste sweetness. This study is currently looking for participants aged 18 and older who do not have major mental health issues, like depression or anxiety, and who are not taking any antidepressant medications. It’s important that participants have no significant health problems that might interfere with the study, such as serious neurological conditions or ongoing effects from COVID-19, including changes in taste.

If you decide to join this study, you will be asked to participate in taste testing to help researchers determine the level of sweetness you can detect. You'll need to be willing to follow all the study procedures, and you will provide your consent to participate. This study is a great opportunity to contribute to our understanding of taste perception, and your involvement could help improve knowledge in this area.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • . Male and female adults of 18 years old and over;
• • Participants without a diagnosis of major depressive disorder (MDD) / anxiety disorder;
• • Participants not taking an antidepressant during the preceding 6 months
• • Not suffering from significant other mental or physical illness, such as confirmed psychosis, end of life care, or any other condition assessed as significant by the Site Investigator;
• • Willing and able to comply with all study-related procedures;
• • Not having COVID 19 or continuing effects of COVID 19 including altered sense of taste;
• • Understands the study requirements and the treatment procedures and is able to provide written informed consent.
• Exclusion Criteria:
• • Taking antidepressant medication currently or during the previous 6 months;
• • Known or suspected hypersensitivity or intolerance to any taste testing solutions, or any of their excipients;
• • A history or presence of neurological or confounding psychiatric conditions (such as stroke, traumatic brain injury, epilepsy, space occupying lesions, multiple sclerosis, Parkinson's disease, vascular dementia, transient ischemic attack, or schizophrenia);
• • Patients with a diagnosis of chronic pain;
• • Pregnancy or possibility pregnancy, or breastfeeding;
• • Participants using supplements containing psychoactive herbs (for example St Johns Wort or 5-HTP (5-Hydroxytryptophan, also known as oxitriptan);
• • Participants regularly using psychoactive stimulants (for example MDMA);
• • Participants unable or unwilling to comply with study procedures.