A Strategy for Gallstone Expulsion Through Dietary Therapy

Launched by HEPATOPANCREATOBILIARY SURGERY INSTITUTE OF GANSU PROVINCE · Nov 19, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating whether a special diet can help people get rid of small gallstones in the gallbladder. The study is taking place at a hospital and is looking for participants who are between the ages of 65 and 75 and have gallbladder stones that are less than 2 millimeters in size. Some people may not be eligible if they have had certain medical procedures, surgeries, or specific health conditions affecting the gallbladder or other parts of the digestive system.

If you qualify to join the study, you will follow a dietary plan that researchers believe may help in expelling these stones. The trial is currently recruiting participants, and everyone involved will not know whether they are receiving the actual dietary therapy or a placebo (a non-active treatment) to ensure fair results. This study aims to see if dietary changes can be a safe and effective way to manage gallstones without surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Gallbladder sludge-like stones with a maximum stone diameter of less than 2 mm
• Exclusion Criteria:
• • History of ERCP (Endoscopic Retrograde Cholangiopancreatography)
• • Previous gallstone removal surgery with gallbladder preservation
• • History of acute or chronic pancreatitis, cholangitis
• • Mirizzi Syndrome
• • History of gastrointestinal surgery
• • Gastrointestinal obstruction
• • Dysfunction of the sphincter of Oddi
• • Gallbladder neck polyps
• • Abnormal gallbladder structure
• • Gallbladder mass
• • Biliary infection or stones
• • Congenital biliary abnormalities
• • Biliary injury or surgery
• • Biliary tumors
• • Gastrointestinal bleeding, liver cirrhosis, or other malignant diseases
• • Significant arrhythmia, bradycardia, or atrioventricular block
• • Severe hypertension, liver or kidney insufficiency
• • Immune, endocrine, hematological, or mental disorders
• • Severe cerebrovascular disease
• • Allergy to relevant foods
• • Pregnant or breastfeeding women
• • Unwillingness or inability to consent to participation