Clinical Comparative Evaluation of the Use of Photodynamic Therapy in Conjunction With the Use of Vitamin D in Management Stage II Grade B Periodontitis Patients

Launched by CAIRO UNIVERSITY · Nov 19, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a treatment method called photodynamic therapy combined with vitamin D to help manage a type of gum disease known as Stage II Grade B periodontitis. This condition can cause gum inflammation and loss of bone around the teeth. The trial aims to see if this combination of treatments can improve the health of the gums and teeth in patients who have a deficiency in vitamin D.

To be eligible for this study, participants must be healthy adults aged 25 years or older, diagnosed with Stage II periodontitis, and showing specific signs of gum and bone health issues. Those who have had recent dental treatments, are taking certain medications, or have conditions that could affect healing will not be included. Participants can expect to receive either the new treatment or standard care while being monitored for their gum health over the course of the trial. This study is currently looking for volunteers, and it’s important to note that anyone taking vitamin D supplements or who has certain health conditions, such as diabetes, will not qualify.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Systemic healthy patients
• • Patients aged \> 25 years
• • Patients suffering from stage II periodontitis with grade B were included in this study, according to 2017 world workshop classification of periodontal disease.
• • Patients with interdental clinical attachment loss (CAL) of 3-4 mm with radiographic evidence of bone loss extending to coronal third of the root.
• • Radiographic bone loss (RBL) will be diagnosed using periapical parallel technique using 6 radiographic images for full mouth (3- radiographic images for maxillary arch and 3- radiographic images for mandibular arch) including anterior, canine region and posterior teeth at baseline for diagnosis.
• • No history of previous periodontal therapy.
• • No taken medications known to interfere healing or periodontal tissue health such as anticonvulsants, calcium channel blockers, or immunosuppressant drugs.
• • No previous periodontal surgery at involved sites.
• • Good oral hygiene and good compliance with the plaque control instructions following initial therapy.
• • Neither taken antibiotics within the last three months nor nonsteroidal anti-inflammatory drugs within the last three months
• • Absence of diseases or conditions that would interfere with wound healing such as diabetes mellitus or coagulation disorders
• Exclusion Criteria:
• • Patients taking Vitamin D as a nutritional supplement were excluded from the study
• • Smoking habits
• • Pregnant and lactating mothers
• • Patients who have been received periodontal surgery in the study area during the last 6 months.