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Search / Trial NCT06702787

Mechanical Thrombectomy in the Middle East and North Africa: Interim Results from the MEMENTO Registry

Launched by MIDDLE EAST NORTH AFRICA STROKE AND INTERVENTIONAL NEUROTHERAPIES ORGANIZATION · Nov 22, 2024

Trial Information

Current as of July 23, 2025

Enrolling by invitation

Keywords

Mechanical Thrombectomy Acute Ischemic Stroke Large Vessel Occlusion Middle East And North Africa Mena Region Endovascular Treatment Cerebral Infarction Brain Ischemia Stroke Management Reperfusion Therapy Neurointervention Cerebrovascular

ClinConnect Summary

Detailed Description Stroke is a leading cause of morbidity and mortality worldwide, with a significant burden in the MENA region due to limited access to advanced stroke care therapies like mechanical thrombectomy (MT). The MEMENTO Registry seeks to collect real-world data on MT practices, outcomes, and accessibility in the MENA region to inform clinical practice and policy. The study includes AIS patients who underwent MT for confirmed LVO or medium vessel occlusion (MeVO), with or without prior intravenous thrombolysis (IV tPA), regardless of age, baseline NIHSS score, or time from sympt...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adults aged 18 years and older (no upper age limit). Diagnosed with acute ischemic stroke due to confirmed large vessel occlusion (LVO) or medium vessel occlusion (MeVO).
  • Underwent mechanical thrombectomy (MT) with or without prior intravenous thrombolysis (IV tPA).
  • Pre-stroke modified Rankin Scale (mRS) score of 0-5. Consent to participate in the registry (by patient or legal representative).
  • Exclusion Criteria:
  • Absence of confirmed LVO or MeVO. Pre-stroke mRS score of 6. Known severe comorbid conditions precluding MT. Inability to obtain informed consent. Patients not treated with MT.

About Middle East North Africa Stroke And Interventional Neurotherapies Organization

The Middle East North Africa Stroke and Interventional Neurotherapies Organization (MENA-SINO) is a leading clinical trial sponsor dedicated to advancing the field of stroke management and interventional neurotherapies across the MENA region. Committed to improving patient outcomes, MENA-SINO collaborates with healthcare professionals, researchers, and institutions to conduct innovative clinical trials that address critical gaps in stroke treatment and prevention. By fostering a multidisciplinary approach and leveraging regional expertise, the organization aims to enhance clinical practices, promote evidence-based medicine, and ultimately contribute to the global body of knowledge in neurovascular health.

Locations

Alexandria, , Egypt

Patients applied

0 patients applied

Trial Officials

ossama yassin MANSOUR, MD, PhD,

Principal Investigator

Alexandria University

farouk Hassan, MD,Phd

Principal Investigator

cairo university, Egypt

Atila Oscan Ozdimar, MD, PhD

Principal Investigator

Eskisehir Osmangazi University

Syed Irteza Hussain, MD

Principal Investigator

Cleveland Clinic Abu Dhabi

Faisal Alghamdi, MD

Principal Investigator

King Abdullah Medical City

Nadia Hammami, MD

Principal Investigator

institut National de Neurologie

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported