A Study of Surgical Techniques During Cystectomy

Launched by MEMORIAL SLOAN KETTERING CANCER CENTER · Nov 21, 2024

Keywords

ClinConnect Summary

This clinical trial is studying two common surgical methods used during a procedure called radical cystectomy, which is performed to treat bladder cancer. The main goal is to find out if using a ureteral stent— a small tube that helps urine drain from the kidney— or a medication called alvimopan, which helps the bowels work again after surgery, can affect patients' recovery. Researchers want to see if these techniques lead to fewer hospital stays and lower infection rates after surgery.

To participate in this study, individuals must be at least 21 years old and scheduled for a radical cystectomy at a specific hospital. There are no major exclusions, but patients on long-term opioid medications are not eligible for the alvimopan part of the study. Participants will be randomly assigned to one of the surgical approaches, allowing doctors to compare the results. This study is actively recruiting patients, and it aims to provide valuable insights into the best practices for surgical care in bladder cancer treatment.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Stent vs. no stent
• • Patients aged ≥21 years who are scheduled to undergo radical cystectomy for treatment of bladder cancer with one of the consenting surgeons at MSK Alvimopan vs. no alvimopan
• • Patients aged ≥21 years who are scheduled to undergo radical cystectomy for treatment of bladder cancer with one of the consenting surgeons at MSK
• Exclusion Criteria:
• • Stent vs. no stent
• • No exclusion criteria Alvimopan vs. no alvimopan
• • Patients on chronic opioid therapy are ineligible to receive alvimopan and will be excluded from this cohort of the trial