Efficacy of Low Glycemic Index Diet Versus Classic Ketogenic Diet in Pediatric Epilepsy Treatment

Launched by MASHHAD UNIVERSITY OF MEDICAL SCIENCES · Nov 21, 2024

Keywords

ClinConnect Summary

This clinical trial is studying two different diets to see which one is more effective in treating children with epilepsy that does not respond to medication. The diets being compared are the Classic Ketogenic Diet, which is very high in fat and can be hard for kids to stick to, and a Low Glycemic Index Diet, which is easier to follow because it includes a wider variety of foods. The goal is to find out if the Low Glycemic Index Diet can help reduce the number of seizures in children as effectively as the Classic Ketogenic Diet.

To participate in the trial, children aged 2 to 18 who have epilepsy and have not found relief from at least two medications can apply. Participants will be randomly assigned to one of the two diet groups. Over three months, researchers will track how often and how long the children experience seizures, and then compare the results between the two diets. The trial is currently recruiting participants, and it’s important to note that children with certain medical conditions or those whose parents do not agree to the study cannot take part. This research could help identify a more manageable diet option for children struggling with epilepsy.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Children between 2 and 18 years old who still have epilepsy despite receiving 2 or more medications
• • Children with genetic disease need to receive ketogenic diet (pyruvate dehydrogenase deficiency and GLUT-1 transporter deficiency)
• Exclusion Criteria:
• • Parents' disapproval of the child's participation in the study Having liver and kidney diseases Doctor's disapproval based on the patient's condition Absolute contraindications to the ketogenic diet