Postoperative Analgesia Between Paravertebral Block and Epidural Block in Esophageal Surgery
Launched by ZHEJIANG CANCER HOSPITAL · Nov 21, 2024
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying two different methods of managing pain after esophageal surgery: a paravertebral block using a new long-lasting anesthetic called liposomal bupivacaine, and a standard epidural block. The goal is to see which method provides better pain relief, helps reduce the need for other pain medications, and improves overall patient satisfaction after surgery.
To be eligible for this trial, participants should be between 18 and 80 years old and scheduled for a specific type of esophageal surgery called thoracoscopic esophagectomy. They should also be in generally good health, without any conditions that would make nerve blocks unsafe. Those who have chronic pain issues or are taking certain medications may not be able to participate. If you choose to take part in this study, you can expect to receive one of the pain management techniques and will be asked to share your experience with pain and recovery after your surgery. This research could help improve pain management options for future patients undergoing similar procedures.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • American Society of Anesthesiologist physical status I-III;
- • Scheduled elective thoracoscopic esophagectomy(three-incision approach);
- • Approved participation before study.
- Exclusion Criteria:
- • Patients with contraindications for local nerve block such as spinal anatomic structure abnormality or local infection of puncture area;
- • Anergic to medications used in this study;
- • Patient have chronic pain;
- • Patient receiving anticoagulants, opioids or have a history of narcotic abuse or alcohol abuse;
- • Inability to complete postoperative pain assessments or questionnaires due to communication barriers or mental disorders;
About Zhejiang Cancer Hospital
Zhejiang Cancer Hospital is a leading medical institution in China, dedicated to advancing cancer research, treatment, and patient care. As a prominent clinical trial sponsor, the hospital focuses on innovative therapies and evidence-based practices to improve outcomes for cancer patients. With a multidisciplinary team of experienced oncologists and researchers, Zhejiang Cancer Hospital is committed to fostering collaboration and leveraging cutting-edge technology in its clinical trials. The institution aims to contribute significantly to the global understanding of cancer and enhance therapeutic options through rigorous research and development initiatives.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Hangzhou, Zhejiang, China
Patients applied
Trial Officials
Jiangling Wang, Ph.D
Principal Investigator
Zhejiang Cancer Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported