Differential Study of Invasive Pituitary Adenomas in the Sellar and Cavernous Sinus Regions

Launched by SHANGHAI ZHONGSHAN HOSPITAL · Nov 23, 2024

Keywords

ClinConnect Summary

This clinical trial is studying invasive pituitary tumors, which are growths located in the pituitary gland that can spread into nearby areas, like the cavernous sinus. Researchers want to understand how these tumors behave differently based on their location by collecting samples from both the tumor and surrounding tissue. They will analyze these samples using advanced techniques to identify molecular differences and understand how these differences might affect the tumor's growth and spread. The goal is to find new markers that could help in understanding the aggressiveness of these tumors and improve future treatments.

To be eligible for this study, participants should be adults aged 18 to 80 who have been diagnosed with invasive pituitary tumors that involve the cavernous sinus. They must also be willing to donate biological samples and health information. Those who are pregnant, breastfeeding, have non-invasive tumors, or have other health issues that would make participation unsuitable cannot join. If you take part in the trial, you can expect to provide tumor samples and health information, and your involvement could help advance our understanding of these complex tumors.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Invasive pituitary tumors involving the cavernous sinus
• • 2. Retrospective inclusion of patients who have signed informed consent forms for the donation of biological samples and health-related information
• • 3. Age range: 18-80 years
• • 4. Subjects are willing to participate in this study
• Exclusion Criteria:
• • 1. Non-invasive pituitary tumors
• • 2. Pregnant or breastfeeding
• • 3. Other conditions deemed unsuitable for participation in this clinical trial as assessed by the physician