Retrospective Study on Leptomeningeal Metastasis of Solid Tumors

Launched by SHANGHAI ZHONGSHAN HOSPITAL · Nov 25, 2024

Keywords

ClinConnect Summary

Experimental Procedure：

1. Case Collection This study collected all cases of leptomeningeal metastasis (LM) diagnosed through cerebrospinal fluid cytology at our center between January 2014 and August 2024. The collected data includes:Demographic information: Age, gender Clinical presentation: Chief complaints, current medical history, past medical history Pathological data: Pathology reports Laboratory findings: Blood lipids, renal function, platelet counts Physical characteristics: Body mass index (BMI), smoking history Surgical records: Detailed records of any surgeries Imaging data: Pr...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients with a previously or recently diagnosed solid tumor in other parts of the body.
• • 2. Detection of metastatic tumor cells in cerebrospinal fluid (CSF) cytology examination.
• • 3. The patient has signed an informed consent form for the donation of biological samples and health-related information.
• • 4. Age between 18 and 80 years.
• • 5. The participant is willing to take part in this study.
• Exclusion Criteria:
• • 1. Presence of a clearly defined single intracranial lesion with a mass effect.
• • 2. Pregnancy or breastfeeding.
• • 3. Any other conditions deemed unsuitable for participation in this clinical trial, as evaluated by the physician.