Comparative Analysis of Sarcopenia in Rehabilitation Outcomes Following Femoral Neck Fracture: a Study in Normal Weight and Obese Study Cohort

Launched by SHMUEL HAROFEH HOSPITAL, GERIATRIC MEDICAL CENTER · Nov 21, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how obesity affects muscle loss and recovery in older adults who have recently suffered a femoral neck fracture, which is a type of hip fracture. The researchers want to understand the prevalence and severity of muscle loss, known as sarcopenia, in normal-weight versus obese patients as they go through rehabilitation after their fracture. They hope this will help improve recovery outcomes for these individuals, as many elderly patients struggle to regain their strength and independence after such injuries.

To participate in this study, individuals must be between 60 and 85 years old and have had a femoral neck fracture within the past year. They also need to be able to understand and sign consent forms. Participants will receive a thorough evaluation of their health, including tests for muscle strength and mobility, and will repeat these assessments after rehabilitation to see how their condition has changed. Throughout the study, all information will be kept confidential, and the procedures involved are non-invasive, meaning they won't require any surgeries or major interventions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age between 60-85
• • Suffered a femoral neck fracture in the last year.
• • Subject willing and able to read, understand and sign an informed consent.
• Exclusion Criteria:
• • Inability to comply with the study protocol or understand and sign an informed consent
• • Diagnosis of a psychiatric disorder prior to the recent femoral neck.
• • Active malignancy
• • History of other neurodegenerative diseases including Alzheimer's disease (AD), Parkinson's disease (PD), Lewy Body Dementia (LBD), Frontotemporal dementia (FTD), Multiple sclerosis (MS), Amyotrophic lateral sclerosis (ALS), Creutzfeld Jacob disease (CJD), Multisystem atrophy (MSA), Pseudobulbar palsy (PSP), Corticobasal degeneration (CBD), Wernicke Korsakoff syndrome
• • Chronic Inflammatory Disorders:(e.g., rheumatoid arthritis, systemic lupus erythematosus).
• • Endocrine Disorders: Individuals with endocrine disorders affecting muscle metabolism (e.g., Cushing's syndrome, hyperthyroidism)
• • Recent Major Surgeries: Participants who had undergone major surgeries other than femoral neck fracture within the last six months