Can Computational Measures of Task Performance Predict Psychiatric Symptoms and Changes in Symptom Severity Across Time

Launched by CALIFORNIA INSTITUTE OF TECHNOLOGY · Nov 21, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how performance on specific tasks can help predict symptoms of mental health conditions like depression, anxiety, and obsessive-compulsive disorder (OCD). Researchers want to understand the relationship between how people perform on these tasks and their mental health symptoms over a year. They will include both healthy individuals and patients with psychiatric diagnoses, recruiting participants through online platforms and UCLA’s psychiatry clinics.

To be eligible, healthy participants must be between 18 and 65 years old and not have any psychiatric diagnoses. Patients can also be in the same age range but must have a diagnosis of depression, anxiety, or OCD. All participants need to be able to understand and complete the tasks and provide informed consent. It's important to note that individuals with certain neurological diseases or psychotic disorders cannot participate. If you join, you can expect to perform some tasks and share information about your mental health over the next year. This study aims to provide valuable insights into the connections between task performance and psychiatric symptoms, which could help improve future treatments.

Gender

ALL

Eligibility criteria

• Inclusion criteria (healthy control participants):
• • Age range of 18 to 65.
• • Not currently having a psychiatric diagnosis determined after psychiatric evaluation by Drs. Tadayon-Nejad and Wei (both are board certified psychiatrists).
• • Ability to understand and perform experimental tasks, i.e. basic ability to communicate and comprehend tasks.
• • Ability to give informed consent.
• Exclusion criteria (healthy control participants):
• • • Prior history and or current diagnosis of neurological disease.
• Inclusion criteria (patients):
• • Age range of 18 to 65.
• • Psychiatric diagnosis of any type of depressive disorders, any type of anxiety disorders or obsessive-compulsive disorder.
• • Primary or comorbid bipolar disorders are allowed but only if not in the acute manic phase.
• • Comorbidity with autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are allowed.
• • Ability to understand and perform experimental tasks, i.e. basic ability to communicate and comprehend tasks.
• • Ability to give informed consent.
• Exclusion criteria (patients):
• • Prior history and or current diagnosis of neurological disease.
• • History or current diagnosis of psychotic disorders.
• • Currently active substance use disorder.