Effect of Intranasal Breast Milk Administration in Preterm Infants

Launched by SELCUK UNIVERSITY · Nov 22, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effects of giving preterm infants breast milk through their nose. Researchers want to see if this method can improve how much oxygen gets to the brain, how well the babies are doing overall, and how quickly they can start feeding normally. The trial is currently looking for participants, specifically preterm infants who weigh more than 1000 grams (about 2.2 pounds) and have a good health score right after birth.

To be eligible, babies need to be able to receive breast milk and not have certain medical conditions that could affect their brain oxygen levels. They also cannot be fully formula-fed or on breathing support. If your baby qualifies, they will receive breast milk through their nose in a safe and monitored setting. This could help improve their health and feeding abilities. If you're interested in learning more or if you think your baby might be a good fit for this study, please reach out to the research team for more information.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Birth weight \>1000 gr,
• • APGAR score \>7 at 5 minutes after birth,
• • Availability of breast milk,
• • No medical diagnosis affecting cerebral oxygenation (intraventricular hemorrhage, cardiovascular and neurological disorders, anemia),
• • No congenital anomalies or chromosomal abnormalities,
• • No congenital anomaly (such as cleft palate) affecting nasal patency.
• Exclusion Criteria:
• • Being able to feed orally in all feedings
• • Being fed entirely on formula milk,
• • Administration of medication via the nasal route,
• • Being intubated or receiving continuous positive air pressure (CPAP) support,
• • Maternal substance abuse, alcohol abuse, HIV infection, untreated active tuberculosis, chemotherapy or radiotherapy treatment,
• • The mother has mastitis, breast trauma, abscesses or is taking any medication that passes into the milk,
• • The mother does not want to express milk.