A Study on Different Treatments for Knee Osteoarthritis Caused by Damaged Roots of the Medial Meniscus.

Launched by SHANGHAI GENERAL HOSPITAL, SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE · Nov 26, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating different treatment options for people with knee osteoarthritis caused by a specific type of meniscus tear called a posterior root tear of the medial meniscus. These injuries can lead to worsening knee problems if not treated properly, so the study aims to find out how various treatments—such as conservative care, surgery to remove part of the meniscus, or repairing the meniscus—affect the knee's cartilage and overall joint health. By using MRI scans, researchers will monitor changes in the knee after these treatments to help determine the best way to slow down arthritis progression.

To participate in this trial, individuals need to be between 50 and 65 years old and diagnosed with a posterior root tear of the medial meniscus that is not too severe. Participants should have good knee movement and be able to complete follow-up MRI scans within two years of their surgery. Those with other knee injuries, infections, or certain health conditions may not be eligible. If you join the study, you can expect to receive one of the treatment options while contributing to important research that could improve care for knee osteoarthritis.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Clinical diagnosis of posterior root tear of the medial meniscus;
• • 2. Patients with K-L classification ≤ grade II;
• • 3. The age range of 50-65 years old;
• • 4. International Cartilage Repair Society (ICRS) Modified Magnetic Resonance Imaging Grading System ≤ Grade 2;
• • 5. International Cartilage Repair Society (ICRS) arthroscopic grading system ≤ grade 2;
• • 6. Knee joint mobility ≥90°;
• • 7. Inversion deformity ≤10°;
• • 8. Must be able to complete follow-up MRI within 2 years after knee meniscus surgery;
• • 9. Must be able to complete clinical data;
• Exclusion Criteria:
• • 1. Can not participate in this study;
• • 2. Patients with concomitant meniscal injuries elsewhere;
• • 3. knee joint infection disease;
• • 4. Osteoporosis disease;
• • 5. Patients with previous history of knee surgery;
• • 6. Knee joint instability disease;
• • 7. Severe KOA disease;
• • 8. Can not cooperate with MRI detection;
• • 9. Cannot tolerate the surgery;
• • 10. Those who cannot tolerate the arthroscopic knee surgery;
• • 11. Neuromuscular system pathology disease;