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Search / Trial NCT06708533

Investigating the Gut Microbiome and Symptomology in IBS

Launched by NOTTINGHAM TRENT UNIVERSITY · Nov 25, 2024

Trial Information

Current as of June 26, 2025

Not yet recruiting

Keywords

Physical Activity Irritable Bowel Syndrome Gut Microbiome Exercise Ibs

ClinConnect Summary

This clinical trial is studying how a regular walking program might help adults with Irritable Bowel Syndrome (IBS) feel better. IBS is a common digestive condition that can cause symptoms like stomach pain, bloating, and changes in bowel habits. The researchers want to find out if participating in a 12-week walking program can reduce the severity of these symptoms compared to people who don’t participate in any activity.

To be eligible for this study, participants must be between 18 and 64 years old and have been clinically diagnosed with IBS. They should also know the specific type of IBS they have, such as constipation-predominant or diarrhea-predominant. If you join the study, you will walk regularly for 12 weeks and visit the university three times for health assessments and to provide some biological samples. It’s important to note that this study is not yet recruiting participants, so keep an eye out if you think this might be something you’d like to be part of!

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Be 18-64 years old
  • Have CLINCALLY DIAGNOSED IBS
  • Know your IBS-SUBTYPE (e.g., constipation, diarrhoea, mixed/alternating)
  • Exclusion Criteria:
  • Pregnant or breastfeeding
  • Organic gastrointestinal conditions (Inflammatory Bowel Disease, Coeliac Disease, Colorectal Cancer)
  • On medication with known influence on gastrointestinal motility (thyroid disease, diabetes mellitus, coeliac disease and neurological disease)
  • Have used antibiotics in the past 3 months
  • Currently using opioid pain medications (except occasional/non-daily use of NSAIDs)
  • Regular consumption of pre- and probiotic foods/supplements
  • Completing more than 300-minutes of PA per week

About Nottingham Trent University

Nottingham Trent University (NTU) is a prominent higher education institution in the UK, renowned for its commitment to advancing research and innovation across various disciplines, including healthcare and clinical trials. With a strong emphasis on interdisciplinary collaboration, NTU leverages its expertise in health sciences to design and conduct rigorous clinical studies aimed at improving patient outcomes and informing public health strategies. The university fosters a dynamic research environment, utilizing state-of-the-art facilities and methodologies to ensure ethical standards and scientific integrity in all its clinical trial endeavors.

Locations

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported