Study on the Effect and Mechanism of Aescine Sodium in the Treatment of Allergic Rhinitis

Launched by CHENG LEI · Nov 27, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a treatment called Aescine Sodium for people with allergic rhinitis, which is a condition that causes symptoms like a stuffy nose, sneezing, and itchy eyes due to allergies. The trial aims to understand how Aescine Sodium can help reduce swelling in the nasal passages and improve symptoms for those who struggle with traditional treatments. Allergic rhinitis can significantly affect daily life, and this research hopes to offer a new option for relief.

To be eligible for the trial, participants must be adults between 18 and 65 years old and diagnosed with allergic rhinitis based on their medical history and specific allergy tests. However, those who have recently taken certain medications or have other nasal or serious health conditions, including pregnant women and smokers, are not eligible to participate. If you join the study, you can expect to receive treatment and be monitored by healthcare professionals to see how well Aescine Sodium works for your symptoms. This trial is a step towards finding better ways to manage allergic rhinitis for those who need more effective solutions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult patients (18-65 years).
• • Patients with allergic rhinitis were diagnosed based on clinical history and positive sensitization tests (skin prick test and/or specific IgE).
• Exclusion Criteria:
• • Received glucocorticoids, immunomodulatory, antihistamine drugs, and other medications that may affect the study results within the last 1 month.
• • Nasal diseases such as upper respiratory tract infections, chronic sinusitis with or without nasal polyps, and nasal sinus tumors.
• • History of nasal sinus surgery.
• • With other immune and allergic diseases.
• • Patients with a combination of severe cardiac, cerebrovascular or pulmonary - diseases, aspirin triad, primary ciliary dyskinesia, immune deficiency, and coagulation disorders.
• • Pregnant women.
• • Smokers.