Cardiovascular Responses in Burn Survivors During Exercise

Launched by UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER · Nov 25, 2024

Keywords

ClinConnect Summary

This clinical trial, titled "Cardiac Responses in Burn Survivors During Exercise," is studying how different cooling methods can help manage body temperature and heart stress during exercise for burn survivors. The researchers want to see if using fans and wetting the skin can make a difference when these individuals exercise in warmer conditions. The trial will include two groups: burn survivors who have healed from significant burns (covering at least 20% of their body) and healthy individuals who have not experienced burns.

To participate, burn survivors must be between 18 and 65 years old, have a serious burn injury that required hospitalization and skin grafting, and be in good health overall. Healthy participants must also be within the same age range and free of significant medical conditions. During the study, participants will be asked to exercise while being monitored to see how well the cooling methods work. This research aims to improve the safety and comfort of burn survivors during physical activities, which is an important step in their recovery and rehabilitation.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria: Non-Burned Individuals
• • Healthy male and female subjects
• • 18-65 years of age.
• • Free of any underlying medical conditions
• • Exclusion Criteria: Non-Burned Individuals
• • Any burn-related injuries resulting in at least one night of hospitalization.
• • Heart disease or any other chronic medical condition requiring regular medical therapy including cancer, diabetes, and hypertension.
• • Abnormalities detected on routine screening
• • Individuals who participate in a structured aerobic exercise training program at moderate to high intensities.
• • Current smokers, as well as individuals who regularly smoked within the past 3 years.
• • Body mass index of greater than 30 kg/m\^2.
• • Pregnant individuals
• • Inclusion Criteria: Burn Survivors
• • Healthy male and female subjects
• • 18-65 years of age.
• • Free of any underlying medical conditions
• • Having a burn injury covering 20% or more of the participant's body surface area; at least 50% of those burn injuries must be full thickness that required skin grafting.
• • Participants must have been hospitalized due to the burn injury for a minimum of 15 days
• • Exclusion Criteria: Burn Survivors
• • Any burn-related injuries resulting in at least one night of hospitalization.
• • Heart disease or any other chronic medical condition requiring regular medical therapy including cancer, diabetes, and hypertension.
• • Abnormalities detected on routine screening
• • Individuals who participate in a structured aerobic exercise training program at moderate to high intensities.
• • Current smokers, as well as individuals who regularly smoked within the past 3 years.
• • Body mass index of greater than 30 kg/m\^2.
• • Pregnant individuals
• • Extensive unhealed injured skin