Trop2-targeting NIR-II Molecular Probe for Breast Cancer Precise Surgery

Launched by YUNNAN CANCER HOSPITAL · Nov 27, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new tool called TTP-ICG, which is designed to help surgeons during breast cancer operations. The goal is to improve the accuracy of removing cancerous tissue and to better identify whether cancer has spread to nearby lymph nodes. By using a special type of imaging that works in the near-infrared range, the TTP-ICG probe can help distinguish between cancerous and healthy tissue in real-time during surgery. This may lead to fewer cases where cancer is left behind after surgery and could reduce complications related to lymph node removal.

To participate in this trial, women aged 18 to 75 who have a breast lump that doctors believe can be surgically removed may be eligible. Participants should be healthy enough for surgery and able to give informed consent. If you join the trial, you can expect to have your tissue examined with the new imaging technique right after it's removed, which will help researchers learn more about how effective this method is. It's important to know that some individuals may not be able to participate if they have serious health issues or other conditions that could complicate the surgery.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Adult patients between 18-75 years of age
• • Female
• • Patients presenting with a breast nodule or mass presumed to be resectable on pre-operative assessment
• • Good operative candidate
• • Subject capable of giving informed consent and participating in the process of consent
• Exclusion Criteria:
• • Patients unable to participate in the consent process
• • Patients had contraindications to surgery, such as serious cardiopulmonary disease, coagulation dysfunction, etc
• • Other conditions that the researcher considers inappropriate to participate in the study