Venous Ultrasound Guided Organ Decongestion in Patients Hospitalized with Acute Decompensated Heart Failure

Launched by OSLO UNIVERSITY HOSPITAL · Nov 28, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new way to help patients with acute decompensated heart failure (ADHF), a condition where the heart can't pump blood effectively, often leading to fluid buildup in the body. The researchers want to see if using a specific ultrasound technique called VExUS, which looks at how well blood is flowing in the veins, can help doctors make better treatment decisions to reduce this fluid buildup compared to standard care. The study will involve 180 patients who will be randomly assigned to either receive the VExUS-guided treatment or standard care, with regular check-ins during their hospital stay.

To be eligible for the trial, participants must be 18 years or older, currently hospitalized with ADHF, and meet certain health criteria, such as having a specific level of a heart-related biomarker in their blood. Throughout the study, participants can expect close monitoring while in the hospital and follow-up calls six months after discharge to evaluate their health. The trial will also keep a close eye on patient safety, checking for any potential side effects or complications. Overall, this research aims to find out if the VExUS method can improve patient outcomes and help manage heart failure more effectively.

Gender

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Eligibility criteria

• Inclusion Criteria:
• • 18 years of age or above
• • Admitted the ward of Department of Cardiology OUH Ullevål with a clinical diagnosis of ADHFdefined by European Society of Cardiology
• • Pro-BNP \> 800 ng/l at first day of admission
• • Capable of giving signed informed consent
• Exclusion Criteria:
• • - Any medical or psychiatric condition which in the opinion of the investigatorprecludes participation