Effect of a Sugar Replacement on Blood Glucose Levels in Healthy Adults

Launched by UNIVERSITY OF ABERDEEN · Nov 28, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a sugar replacement called Oligomate® on blood sugar levels after meals in healthy adults. The goal is to see if using Oligomate® instead of regular sugar in a drink can help lower blood sugar spikes that occur after eating. High blood sugar levels, especially after meals, can increase the risk of diabetes and heart disease, so finding ways to manage this is important for overall health.

To participate in this study, you need to be a healthy adult between the ages of 18 and 65 with a body mass index (BMI) between 18.5 and 26. You cannot have diabetes or any major health issues, and you should not be taking certain medications that affect blood sugar levels. If you join the study, you will drink a beverage with either Oligomate® or regular sugar and have your blood tested at different times to see how your blood sugar and insulin levels change. This is an exciting opportunity to help researchers learn more about how to manage blood sugar levels and potentially improve health outcomes for everyone.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Healthy Men or Women
• • Body Mass Index (BMI) 18.5-29.9 kg/m\^2
• • Between 18 and 65 years of age
• • Compliant (i.e., understands and is willing, able, and likely to comply with the experimental procedure and safety guidelines)
• • Able to provide informed consent
• • Premenopausal women must have a regular cycle or be on hormonal contraception.
• Exclusion Criteria:
• • Diabetes mellitus (all types including gestational diabetes)
• • HbA1c result over the study limit \[healthy range of between 4% and 5.9%\]
• • Endocrine disease (e.g., Cushing's syndrome)
• • Any food allergy or intolerance, or following Vegan diet
• • Medications that increase blood glucose (e.g., steroids, protease inhibitors, antipsychotics, antihypertensives, statins, diuretics, nicotinic acid, etc.)
• • Medications that lower glycemia (e.g., anti-hyperglycaemics, insulin, beta- blockers, etc.)
• • Medication affecting glucose regulation, appetite, and/or digestion/absorption of nutrients, antibiotics
• • Major medical or surgical event requiring hospitalization in the previous 3 months
• • Pregnant or lactating
• • Participation in another clinical/supplementation trial or actively trying to reduce body weight
• • Unable to comply with experimental procedures and safety guidelines
• • Unable to give consent
• • Smokers
• • Travel during the study period