Role of Acute Phase Proteins In Diagnosis of Immune Thrombocytopenia

Launched by SOHAG UNIVERSITY · Nov 28, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how certain proteins in the blood, known as acute phase proteins, can help diagnose a condition called immune thrombocytopenia (ITP). ITP is a disorder where the body mistakenly destroys its own platelets, which are important for blood clotting. The trial is looking for patients, aged 1 to 50 years, who have a platelet count below 100,000 per microliter and have been diagnosed with ITP based on specific tests of the bone marrow. Participants in the study will help researchers understand if measuring these proteins can improve the diagnosis and management of ITP.

If you or your child are eligible, you may be invited to participate in this study. During the trial, participants will undergo blood tests to measure the levels of these proteins and help researchers learn more about their role in ITP. It’s important to note that individuals with certain other medical conditions or those who have received specific treatments, such as chemotherapy or antibiotics, will not be included in this study. This research may offer valuable insights into better ways to diagnose and treat ITP in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with platelet less than 100 × 109/L diagnosed as immune thrombocytopenia by bone marrow findings .
• • Age of patients : from 1 year to 50 years.
• Exclusion Criteria:
• * - Other causes of thrombocytopenia as:
• • Hypersplenism.
• • Bone marrow diseases including : aplastic anemia, leukemia and myelodysplastic syndromes.
• • Cancer treatments like chemotherapy and radiation therapy.
• • Exposure to toxic chemicals as arsenic and benzene.
• • Medications to treat bacterial infections (antibiotics)and treat seizures or blood thinner heparin.