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Search / Trial NCT06716489

Aerobic Exercise and Its Impact on Sensory, Musculoskeletal, and Psychosocial Aspects in Migraine

Launched by UNIVERSITY OF SAO PAULO · Nov 28, 2024

Trial Information

Current as of June 26, 2025

Not yet recruiting

Keywords

Migraine Aerobic Exercise Sensory Perception Exercise Headache Disability Musculoeskeletal Alterations Quality Of Life Neck Pain Cervical Pain Sensory Thresholds Psychosocial Factors Physical Fitness Exercise Intervention Central Sensitization Physical Therapy Migraine Management Non Pharmacological Treatment Clinical Trial Headache Relief Sensitization

ClinConnect Summary

This clinical trial is studying how a 16-week aerobic exercise program can help women aged 18 to 40 who suffer from migraines. The goal is to see if regular exercise can reduce the frequency and severity of migraine attacks, as well as improve aspects like physical fitness, neck pain, and overall quality of life. Participants will take part in treadmill sessions three times a week, tailored to their fitness levels, and will undergo various assessments to measure changes in their headache-related disabilities and sensory perception.

To be eligible for the study, women must be diagnosed with migraines that occur between three and eight days each month. They should not have other types of headaches, serious medical conditions, or be engaging in regular exercise. This study aims to find out if aerobic exercise can be a safe and effective way to manage migraines, which could lead to more accessible treatment options for those suffering from this condition.

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Women aged between 18 and 40 years.
  • Diagnosed with migraine by an experienced neurologist specialized in headaches, following the criteria of the International Classification of Headache Disorders (ICHD).
  • Frequency of headache between 3 and 8 days per month, to ensure adherence to the treatment.
  • Exclusion Criteria:
  • Presence of any other type of concurrent headache.
  • Medical conditions affecting sensitivity and autonomic modulation, such as peripheral neuropathies, autonomic disorders, severe neurological diseases, and others.
  • Conditions that prevent physical activity, such as severe musculoskeletal injuries, cardiovascular diseases, or related conditions.
  • Premature ovarian failure.
  • Regular physical exercise in the past year.
  • Body Mass Index (BMI) above 30.0.
  • Smokers or individuals using drugs that interfere with sensitivity and cardiac modulation (e.g., beta-blockers).
  • Abuse of abortive medications.

About University Of Sao Paulo

The University of São Paulo (USP) is a prestigious public research university located in Brazil, renowned for its commitment to advancing knowledge and innovation in various fields, including medicine and health sciences. As a clinical trial sponsor, USP leverages its extensive academic resources, interdisciplinary expertise, and state-of-the-art facilities to facilitate groundbreaking research aimed at improving patient outcomes and addressing critical health challenges. The university's strong emphasis on ethical standards and regulatory compliance ensures that all clinical trials are conducted with the highest integrity, fostering collaboration among researchers, healthcare professionals, and the broader community to enhance scientific discovery and translate findings into practical applications.

Locations

Ribeirao Preto, São Paulo, Brazil

Ribeirao Preto, , Brazil

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported