Non-invasive Preoperative Tissue Evaluation in Head and Neck Tumor Patients Using Multispectral Optoacoustic Tomography (MSOT)

Launched by UNIVERSITY OF ERLANGEN-NÜRNBERG MEDICAL SCHOOL · Nov 29, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new imaging technology called Multispectral Optoacoustic Tomography (MSOT), which uses laser light to look at how well oxygen is flowing in different tissues of the body. The researchers want to find out if patients with head and neck cancer have less effective blood flow in their tissues compared to healthy individuals. This is important because good blood flow is crucial for any tissue that might be used for reconstructive surgery, and some cancer patients may have issues due to factors like smoking.

The trial is open to two groups of people: those with diagnosed head and neck cancer and healthy adults. To participate, individuals should be between 65 and 74 years old and must not be pregnant, breastfeeding, or have tattoos in the areas being studied. Participants will undergo scans on common areas of their bodies, such as the back, arms, and legs, to measure muscle oxygenation. This information will help researchers understand how cancer and other factors might affect tissue health, which is vital for planning successful surgeries.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Cohort 1: Histopathological diagnosed head and neck tumor patients.
• • Cohort 2: Healthy adults.
• Exclusion Criteria:
• • Pregnancy / breastfeeding
• • ink / tattoo in the areas of interest (upper back, distal forearm, upper and lower leg)
• • missing consent form
• • Cohort 2: Chronical abuse of alcohol and nicotine.