Cancer and Aging Research Group (CARG) Chemotherapy Toxicity Risk Scores in Older Adults With Cancer in China

Launched by RENJI HOSPITAL · Dec 1, 2024

Keywords

ClinConnect Summary

This clinical trial is looking to understand how chemotherapy affects older cancer patients in China, specifically those who are over 70 years old. The researchers want to see if a special scoring system called the CARG chemotherapy toxicity risk score can help predict how likely these patients are to experience side effects from chemotherapy. To participate, patients need to be 70 or older, have a confirmed diagnosis of a solid tumor, and be able to communicate in Chinese. They should also be admitted to the hospital for a new chemotherapy treatment.

Participants in this trial will answer questions based on the CARG tool to help researchers gather important information about their experiences with chemotherapy. This study is currently recruiting, and it’s an opportunity for older adults with specific health conditions to contribute to our understanding of chemotherapy side effects in their age group. It’s important to note that patients with certain conditions, like severe infections or other serious health issues, will not be eligible for this trial.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age≥ 70 years old
• • Confirmed diagnosis of solid tumor (any stage)
• • ECOG-PS score 0-2 points
• • Admission to the hospital for a new chemotherapy regimen (initial or change)
• • Patients need to have the ability to read and write, or communicate in Chinese
• • The patient must have the ability to give informed consent.
• Exclusion Criteria:
• • Patients who are on immunotherapy and/or targeted therapy only
• • Patients with hematologic malignancy
• • Patients with severe infections (sepsis, severe respiratory tract infections, severe urinary tract infections, severe abdominal infections, etc.).
• • Patients with severe heart, liver, and kidney dysfunction or failure