Tissue Analysis of Liver Grafts as a Predictor of Transplant Outcome.

Launched by IRCCS AZIENDA OSPEDALIERO-UNIVERSITARIA DI BOLOGNA · Dec 1, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how examining liver tissue from donors and recipients can help predict the success of liver transplants. Researchers are particularly interested in understanding the changes that happen to the liver during a special preservation process called HOPE, which is used before transplantation. By looking closely at these changes, the goal is to develop more personalized treatment methods that could improve transplant outcomes for patients in the future.

To participate in this trial, donors need to have enough liver tissue available for testing and must have undergone the HOPE procedure. Recipients must be at least 18 years old and also provide enough tissue for analysis. There are no specific exclusions for this trial, so if you meet the criteria, you might be eligible to join. Participants can expect to contribute to important research that may help enhance the success rates of liver transplants for others down the line.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * For Donors:
• • Availability of enough tissue for histological, immunohistochemical and RT-PCR analysis.
• • HOPE performed on the liver graft prior to transplantation.
• * For Recipients:
• • Availability of enough tissue for histological, immunohistochemical and RT-PCR analysis.
• • Age greater than/equal to 18 years.
• Exclusion Criteria:
• • None