Variation in Drug Interactions in People With HIV (PLWH) Aged 60 Years and Older.

Launched by IRCCS AZIENDA OSPEDALIERO-UNIVERSITARIA DI BOLOGNA · Dec 1, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating how different medications may interact with each other in older adults living with HIV. As people with HIV are living longer due to effective treatments, many are also dealing with other health issues that require additional medications. This study focuses on individuals aged 60 and older who are currently on a specific HIV treatment regimen (bictegravir/emtricitabine/tenofovir alafenamide) and have other non-infectious health conditions that need treatment.

To be eligible for this study, participants must be over 60 years old, have other health issues being treated with medication, and be currently taking the specified HIV regimen. The trial will monitor any significant interactions between their HIV medications and those prescribed for other conditions. Participants can expect to share their medical history and medication details, and their experiences may help improve understanding of how to manage treatments safely for older adults with HIV.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age \> 60 years
• • Non-infectious comorbidities receiving drug therapy
• • Receiving BIC/TAF/FTC therapy at the time of of enrollment
• Exclusion Criteria:
• • Genotypic resistance testing that present or past evidence of viral resistance to the integrase inhibitor class, to emtricitabine or to tenofovir
• • Severe acute infectious disease