Effect of Limb Occlusion Pressure Attainment on Cardiovascular, Perceptual, and Performance Responses

Launched by TERI HERBERGER · Dec 2, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how a specific technique called limb occlusion pressure, which involves restricting blood flow to the limbs, affects exercise performance and muscle health. The researchers want to understand how this technique works when people are lying down, sitting, or standing, and how it influences heart health, blood pressure, and muscle growth. The trial is not yet recruiting participants, but it aims to include physically active individuals aged between 65 and 74 who have been maintaining a stable weight and have regular menstrual cycles if they are women.

To be eligible for this study, participants should be in good health and not have certain medical conditions like high blood pressure, diabetes, or heart disease. They should also not be taking medications that could affect the study results or have had recent surgeries. Participants can expect to engage in exercises while researchers monitor their body responses, helping to gather important information about how this method could improve fitness and heart health. If you think you might be eligible or are interested in how these findings could benefit your health, keep an eye out for more information as the study begins!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Physically active (\> 1,000 MET/min/wk) for at least six months. Weight stable for previous 6 months (+/-2.5 kg) Female subjects only- reported regular menstrual cycles for the last 2 years
• Exclusion Criteria:
• • 1. BP\>140/90 mmHg
• • 2. BMI\>40 kg/m2
• • 3. Diabetes
• • 4. Familial hypercholesterolemia
• • 5. Past or current history of CHD, stroke or major CVD events. Respiratory diseases (not including asthma), endocrine or metabolic, neurological, or hematological disorders that would compromise the study or the health of the subject.
• • 6. Women must not be pregnant, plan to become pregnant during the study, or be nursing
• • 7. Active renal or liver disease
• • 8. All medications and supplements that influence dependent variables\*
• • 9. Recent surgery \< 2 months
• • 10. Alcohol abuse
• • 11. Sleep apnea
• • 12. Claustrophobia