Intraosseous Versus Submucosal Dexamethsone Injection in Third Molar Surgery
Launched by SERVICES INSTITUTE OF MEDICAL SCIENCES, PAKISTAN · Dec 2, 2024
Trial Information
Current as of May 21, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at two different ways to give a medication called dexamethasone to patients having their wisdom teeth (third molars) removed. The researchers want to find out if injecting dexamethasone directly into the bone (intraosseous) is more effective in reducing pain and swelling after surgery compared to injecting it under the gum (submucosal). They will also check if this method helps patients open their mouths wider after the procedure. Participants will be monitored on the 3rd and 7th day after surgery to assess their pain levels, swelling, and mouth opening.
To be eligible for this study, participants must be between 18 and 35 years old and scheduled for wisdom teeth surgery. However, individuals with certain health issues, like uncontrolled diabetes or high blood pressure, or those with specific dental conditions or past medical treatments that could affect the results are not eligible. This trial is not yet recruiting, but it aims to provide important information that could improve post-surgery care for future patients.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients undergoing mandibular third molar surgery
- • Age 18 to 35 years
- • Male and female
- Exclusion Criteria:
- • Uncontrolled systemic medical problems including diabetes and hypertension
- • Presence of any cyst, tumor, or other pathological condition in the molar area
- • Presence of any craniofacial anomalies, congenital deformities or syndromes
- • Patients with known adverse effects of steroid use
- • Previous history of orthodontic treatment
- • Have a pain disorder or taking pain medications
- • Pregnant and lactating mothers
About Services Institute Of Medical Sciences, Pakistan
The Services Institute of Medical Sciences (SIMS) in Pakistan is a prominent medical institution dedicated to advancing healthcare through rigorous research and clinical trials. With a mission to enhance medical knowledge and improve patient outcomes, SIMS engages in a wide range of clinical studies across various specialties. The institute is committed to adhering to international ethical standards and regulatory guidelines, ensuring the integrity and quality of its research endeavors. By fostering collaboration among healthcare professionals and academic researchers, SIMS aims to contribute significantly to the medical field and promote evidence-based practices in healthcare delivery.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Lahore, Punjab, Pakistan
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported