Modeling Blood Management and Hemolytic Risk in Pediatric Heart Surgery

Launched by BOSTON CHILDREN'S HOSPITAL · Dec 3, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how to manage blood transfusions for children undergoing heart surgery. The researchers want to find out the best amounts and types of blood products to give to these young patients during surgery. They also hope to create a mathematical model that could help predict how much blood a child might need, which could improve their care and treatment during heart surgery.

To be eligible for this study, participants must be children under 18 years old who are scheduled for heart surgery at Boston Children's Hospital and will be placed on a heart-lung machine during the procedure. However, children with certain blood disorders or abnormal blood clotting will not be included. This trial is not yet recruiting participants, but it aims to help improve blood management practices in pediatric heart surgery, ultimately leading to better outcomes for young patients. If your child meets the criteria, this study could offer valuable insights into their care during surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • pediatric patients under 18 years of age undergoing cardiac surgery with clear prime on cardio-pulmonary bypass (CPB) at Boston Children's Hospital (BCH).
• Exclusion Criteria:
• • patients with known hemolytic disorders, patients on nitric oxide preoperatively, and patients found to have abnormal coagulation on routine preoperative assessment. Patients receiving heparin, American Society of Anesthesia (ASA) status, apixaban, warfarin, or bivalirudin held appropriately (i.e. for elective surgery) will not be excluded