Thulium Fiber Laser (TFL) vs Thulio Pulsed Thulium:YAG (p-Tm:YAG)

Launched by UNIVERSITY OF CALIFORNIA, SAN DIEGO · Dec 3, 2024

Keywords

ClinConnect Summary

This clinical trial is exploring two different types of laser systems—Thulium Fiber Laser (TFL) and Thulio Pulsed Thulium:YAG (p-Tm:YAG)—to see how effectively they can break up kidney stones during a procedure called ureteroscopy. This treatment is used for patients who have kidney stones that are between 7 to 20 mm in size. The study is currently looking for participants who are between 65 and 74 years old and are suitable candidates for this type of surgery.

To be eligible for the trial, participants should have one or more kidney stones of the appropriate size and should be able to consent to the procedure. It’s important for potential participants to know that certain conditions, like having other stones in the ureter or a history of specific surgeries, may exclude them from the study. If you join this trial, you will help researchers understand which laser system works better for treating kidney stones, potentially improving treatment options for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Solitary renal stone 7 to 20 mm in size or in the case of multiple stones the conglomerate diameter (additive maximal diameter of all stones on axial imaging of computed tomography) of 7-20 mm is required
• • Must be a suitable operative candidate for flexible ureteroscopy per American Urological Association guidelines
• • Must be able to give consent
• • Bilateral ureteroscopy will be permitted but only the first side (per surgeon discretion) will be included in the study
• • Surgeons participating in the study must be urological attending surgeons or fellows with subspecialty training in Endourology
• Exclusion Criteria:
• • Concomitant stones in the ureter
• • Prior ipsilateral upper urinary tract reconstructive procedures or history of ipsilateral ureteral stricture
• • Prior radiotherapy to the abdomen or pelvis
• • Neurogenic bladder or spinal cord injury
• • Pregnancy
• • Untreated UTI