Integrating Pain-CBT Into an mHealth Analgesic Support Intervention for Patients With Chronic Pain From Advanced Cancers

Launched by DANA-FARBER CANCER INSTITUTE · Dec 3, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new smartphone app called STAMP+CBT, which aims to help people with chronic pain caused by advanced cancer. The app combines support for managing pain with psychological strategies, known as Cognitive Behavioral Therapy (CBT), to improve patients' overall well-being. The goal is to make it easier for patients to manage their pain and improve their quality of life.

To participate in this study, you need to be at least 22 years old and have an active cancer diagnosis that is causing chronic pain (with a pain score of more than 4 on a scale of 0-10). You must also be using a smartphone (either an iPhone or Android) and have a prescription for at least one opioid medication to treat your cancer-related pain. The trial is currently not recruiting participants, and it is important to note that those who are in hospice care, recently hospitalized, or unable to consent will not be eligible. If you join the study, you can expect to use the app and take part in activities designed to help manage your pain more effectively.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 22 years
• • Patient diagnosed with an active cancer diagnosis (locally advanced solid tumor malignancy, multiple myeloma, or other advanced hematologic malignancy), either undergoing active treatment or receiving treatment for an advanced cancer or are receiving supportive/palliative care
• • Chronic pain related to cancer or treatment (\> pain score of 4 on a 0-10 scale)
• • Has an active prescription for at least one opioid medication to treat their cancer pain (i.e. not for post-surgical pain)
• • Own/use a compatible smartphone (iPhone or Android)
• Exclusion Criteria:
• • Patients in survivorship: patients who have completed their treatment regimens, are not actively receiving treatment for an advanced cancer, or have a cancer that is in remission
• • Cognitive impairment that would interfere with study participation, as judged by treating clinician (e.g. delirium, dementia)
• • Inability to speak English (the intervention has not yet been translated to Spanish)
• • Currently in CBT treatment
• • Enrolled in hospice
• • Currently hospitalized
• • Use of transmucosal fentanyl, given safety concerns and ongoing risk mitigation program required to prescribe these (TIRF REMS)
• • Pain primarily related to a recent surgery (within the last 2 weeks)
• • Conditions that hinder smartphone use
• • The study will exclude adults who are unable to consent, individuals who are not yet adults (infants, children, teenagers), pregnant women, and prisoners.