Study of Pneumococcal Carriage in RSV Bronchiolitis in Infants Aged 6 to 18 Months

Launched by ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS · Dec 3, 2024

Keywords

ClinConnect Summary

This clinical trial is looking into how the respiratory virus RSV (respiratory syncytial virus) may be linked to infections caused by a bacteria called Streptococcus pneumoniae in infants. Specifically, the study will compare infants with RSV infections who have bronchiolitis (a lung infection causing wheezing and difficulty breathing) to healthy infants who do not have RSV. The researchers want to understand how many of these infants carry the bacteria and what types of the bacteria are present.

To be eligible for the study, infants must be between 6 and 18 months old and either have bronchiolitis during the RSV season or be healthy without an RSV infection. They should not have any chronic illnesses or a history of bronchiolitis. Parents will need to give consent for their child to participate. The trial is currently not recruiting participants, so it’s not yet open for enrollment. If eligible, participants can expect to undergo tests that will help researchers gather important information about the relationship between RSV and bacterial infections, which may improve future treatments for these conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Infants aged 6 months to 18 months inclusive
• • With bronchiolitis during RSV epidemic season (bronchiolitis group) or without evidence of RSV viral infection (healthy group)
• • No chronic illness
• • No history of bronchiolitis
• • Signed consent from parents or legal guardians
• • Patient affiliated to a social security scheme
• Exclusion Criteria:
• • Chronic respiratory illness
• • Medical history of bronchiolitis or newborn asthma
• • Treatment with immunosuppressants
• • Patient on AME