Comparison of the Efficacy of Intraperitoneal Instillation of Fentanyl Versus Nalbuphine As Adjuvants to Bupivacaine for Postoperative Pain Relief in Patients Undergoing Laparoscopic Cholecystectomy

Launched by ASSIUT UNIVERSITY · Dec 4, 2024

Keywords

ClinConnect Summary

This clinical trial is studying two different pain relief options for patients undergoing laparoscopic cholecystectomy, which is a surgery to remove the gallbladder. Specifically, it compares the effectiveness of two medications, fentanyl and nalbuphine, when added to a local anesthetic called bupivacaine. The goal is to find out which combination provides better pain relief after surgery, as managing pain effectively is important for recovery.

To participate in this trial, you must be over 18 years old and generally healthy, falling within specific risk categories set by the American Society of Anesthesiologists. However, some individuals may not qualify, such as those with a high body weight, certain medical conditions, or those who are pregnant. If you decide to join, you can expect to receive one of the pain relief options during your surgery and will be monitored for how well it works afterward. This trial is not yet recruiting participants, but it aims to help improve pain management strategies for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age \>18 years
• • Both sex
• • Patients who were in risk-scoring groups I-II of the American Society of Anesthesiologists (ASA)
• Exclusion Criteria:
• • • Patient's refusal.
• • body mass index (BMI) ≥40 kg/m2.
• • History of hypersensitivity to the drugs being evaluated
• • Inability to comprehend postoperatively the pain assessment scale/neuropsychiatric disorders.
• • chronic use of opioids and opioid addiction
• • Patients with acute cholecystitis
• • Carcinoma of gall bladder
• • Pregnant female
• • Bleeding disorders