Optimal PERioperative Antiplatelet Therapy Investigation ON Abdominal Surgery After Coronary Stent Implantation

Launched by KYOTO UNIVERSITY · Dec 4, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how continuing to take aspirin before and after abdominal surgery affects patients who have had a coronary stent placed in their heart. The goal is to find out if continuing aspirin helps improve health outcomes for these patients during their surgery and recovery. The study is currently recruiting participants, and anyone aged 18 or older with a history of coronary stenting who will be undergoing abdominal surgery may be eligible to join.

To participate, you need to be on a single antiplatelet medication like aspirin, but if you are on multiple antiplatelet drugs or blood-thinning medications, you won’t qualify. Additionally, if you have certain health issues that put you at high risk of bleeding or have had a serious problem with your stent in the past, you also won’t be able to take part. If you join the trial, you will be monitored closely to see how continuing aspirin affects your surgery and recovery. This study aims to provide important information that could help improve care for patients like you in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with a history of coronary stenting and scheduled for abdominal surgery
• • Patients on a single antiplatelet agent
• Exclusion Criteria:
• • Patients on dual antiplatelet therapy (DAPT)
• • Patients on anticoagulation therapy
• • Patients with a history of stent thrombosis
• • Patients with CHADS2 score \>= 5
• • Patients at extremely high risk of bleeding and unable to continue preoperative aspirin
• • Patients incapable of consent, including those under 20 years of age
• • Other patients for whom either discontinuation or continuation of antiplatelet agents is deemed inappropriate by the attending physician