Antidiabetic Effect of Olive Pomace Oil

Launched by INSTITUTO DE CIENCIA Y TECNOLOGÍA DE ALIMENTOS Y NUTRICIÓN · Dec 6, 2024

Keywords

ClinConnect Summary

This clinical trial is studying whether adding olive pomace oil to the diets of people with type 2 diabetes or those at risk of developing diabetes (like prediabetic individuals) can help manage their blood sugar levels. Researchers want to find out if this oil can prevent spikes in blood sugar after meals, lower fasting blood sugar levels, and improve overall blood sugar control and other health issues related to diabetes, such as high cholesterol or inflammation. To do this, they will compare the effects of olive pomace oil with another type of oil called high-oleic acid sunflower oil.

To participate in the study, individuals should have a fasting blood sugar level between 100-126 mg/dL or have a higher level if they are already diagnosed with diabetes. Participants will go through a series of dietary changes over about five months, including eating specific oils on bread and undergoing regular check-ups. They will also keep track of their physical activity and any medications they take. This trial is open to anyone aged 18 to 70, and it’s important to note that people with certain health conditions, dietary restrictions, or who are pregnant cannot participate.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Fasting blood glucose between 100-126 mg/dL and/or
• • Glycated haemoglobin (HbA1c) between 5.7-6.4% and/or
• • Diabetic persons with Fasting blood glucose \>126 mg/dL and/or
• • Diabetic persons with Glycated haemoglobin (HbA1c) \> 6.4%
• Exclusion Criteria:
• • Kidney or liver diseases
• • Gastrointestinal diseases (irritable bowel syndrome, Crohn disease, chronic bowel inflammation)
• • Food allergies/intolerances
• • Vegetarians/vegans
• • Smoking
• • Pregnant or lactating women
• • On prescription drugs other than for hypertension/thyroid/dyslipidemia/glucose control, or changes in dosage in the last 3 months
• • Consumption of vitamins, dietary supplements or nutraceuticals