Personalized Treatment of Refractory BPPV

Launched by HOSPITAL CLINICO UNIVERSITARIO DE SANTIAGO · Dec 8, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new, personalized approach to treat patients with a common type of vertigo called Benign Paroxysmal Positional Vertigo (BPPV), which often doesn’t respond to standard treatments. While most people with BPPV can find relief through specific head movements, about 12.5% continue to experience symptoms despite multiple attempts. This study aims to tailor treatments to each patient’s unique inner ear structure using advanced imaging and simulation techniques to create customized maneuvers.

To be eligible for this trial, participants should be aged between 65 and 75 and have been diagnosed with BPPV that has not improved after trying standard repositioning techniques at least three times. If enrolled, participants will be divided into two groups: one will receive regular treatments, while the other will get personalized treatments designed for their specific condition. The study will monitor how well each approach resolves vertigo symptoms and how it affects patients' quality of life. This trial is currently recruiting participants, and it’s important to note that those with certain cognitive impairments or other health issues may not be able to participate.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * A. Diagnosed with BPPVp according to the Barany Society criteria:
• • 1. Recurrent episodes of vertigo or positional instability, triggered by lying down or turning the head in the supine position.
• • 2. Episodes lasting less than 1 minute.
• • 3. Positional nystagmus observed after a latency period during the Dix-Hallpike test (DHT), with an upward vertical component and a torsional component (clockwise on the left side and counterclockwise on the right).
• • 4. Symptoms not explained by any other cause.
• • AND
• • B. Refractory to otolith repositioning maneuvers (Epley and/or Semont maneuvers), with persistence of symptoms after three attempts.
• Exclusion Criteria:
• • Cognitive impairment that prevents understanding of their condition and the required procedures.
• • Pathological conditions that hinder the execution of the maneuvers.
• • BPPV involving canals other than the posterior canal or bilateral posterior canal involvement.
• • Low educational level, which may impede understanding of the procedures and informed consent.