Quantitative Margin Assessment Using High-resolution Positron Emission Tomography - Computed Tomograhy

Launched by UNIVERSITY MEDICAL CENTER GRONINGEN · Dec 9, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a new type of medical imaging called high-resolution mobile PET-CT scanning. The goal is to see how well this technology can help doctors check the edges of tumors during surgeries for oral squamous cell carcinoma, soft tissue sarcoma, and osteosarcoma. By doing this, the trial aims to determine if the scanner can accurately predict whether all the cancer has been removed, which is important for successful treatment.

To participate, individuals need to be at least 18 years old and have a confirmed diagnosis of one of the specified cancers that require surgery. They should also be able to understand the study and provide written consent. However, certain individuals may not be eligible, such as those who have had previous radiation treatment in the affected area or have specific medical conditions that could affect their participation. This trial is currently not recruiting participants, but it represents an important step in improving surgical outcomes for patients with these types of cancer.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥18 years.
• • Patient is confirmed with oral squamous cell carcinoma, soft tissue sarcoma or osteosarcoma.
• • Patient is indicated to undergo curative surgery of the primary tumor.
• • Patient is estimated compliant for study participation by the investigator.
• • Written informed consent.
• Exclusion Criteria:
• • Medical or psychiatric conditions that compromise the patient's ability to give informed consent;
• • Patient has previously received radiotherapy of the primary tumor region;
• • Patient has participated in other clinical studies with radiation exposure of more than 1 mSv in the past 12 months;
• • A blood glucose level over 200 mg/dL on the day of surgery.
• • Pregnancy or lactation.