Effect of Different Root Canal Sealers on Postoperative Pain
Launched by DICLE UNIVERSITY · Dec 6, 2024
Trial Information
Current as of July 09, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how different materials used to seal root canals affect pain after treatment. The researchers want to find out which root canal sealer causes the least discomfort for patients. Seventy-two people between the ages of 18 and 65, who have a single-rooted tooth needing treatment but are not currently experiencing pain, will be invited to participate. They will be randomly divided into three groups, with each group receiving a different type of root canal sealer during their treatment.
Participants can expect to have their tooth treated in one appointment using a specific technique for filling the root canal. After the procedure, they will be asked to rate their pain on a scale from 0 to 10 at several times over the next week. The study aims to help determine which sealing material is the most comfortable for patients following a root canal procedure. To be eligible, participants should have good oral hygiene and not have used any pain medication recently, among other criteria.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients aged 18-65 years
- • Patients who agreed to participate in this study
- • Patients with single-canal, single-rooted teeth diagnosed with asymptomatic irreversible pulpitis due to trauma or deep carious lesions and patients with single-canal, single-rooted teeth referred for endodontic treatment for prosthetic reasons
- • Patients with asymptomatic teeth
- • Patients who have not used any analgesic, anti-inflammatory, or antibiotic drugs in the last 7 days
- • Patients with good oral hygiene
- • Patients with a sustained positive response to cold test and electric pulp test
- • Patients with healthy periapical tissues (to be confirmed by periapical radiography)
- Exclusion Criteria:
- • Patients who refused to participate in this study
- • Patients with medical problems (patients with immunosuppressive/systemic diseases, patients on medication)
- • Patients with negative responses to thermal and electrical pulp tests
- • Patients with advanced periodontal disease (probing depth \>4 mm)
- • Patients with preoperative percussion and palpation of the involved tooth
- • Open apex, presence of calcification, presence of resorption
- • Patients requiring endodontic treatment of more than one tooth
- • Patients with allergic sensitivity to materials and agents to be used during root canal treatment
- • Patients with allergic sensitivity to local anesthetics
- • Patients with systemic or allergic sensitivity to NSAIDs
- • Pregnant and lactating patients
- • Teeth that cannot be restored due to excessive material loss in the coronal structure
- • Overenstrumentation (extension of gutta-percha or root canal sealer beyond the radiographic apex) or short filling (more than 2 mm below the radiographic apex )
- • Patients who develop acute exacerbations after the procedure
About Dicle University
Dicle University is a prominent academic institution located in the southeastern region of Turkey, dedicated to advancing medical research and education. With a strong commitment to improving healthcare outcomes, Dicle University actively sponsors clinical trials that aim to explore innovative treatments and enhance patient care. The university's multidisciplinary approach fosters collaboration among researchers, healthcare professionals, and students, ensuring that clinical studies are conducted with rigor and integrity. Through its clinical trial initiatives, Dicle University strives to contribute valuable insights to the scientific community and support the development of effective therapeutic interventions.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Diyarbakir, , Turkey
Patients applied
Trial Officials
Merve Yeniceri Ozata, Assoc Prof
Study Director
Dicle University, Faculty of Dentistry, Department of Endodontics
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported