Dopamine and Brain Computer Interface
Launched by MAX PLANCK INSTITUTE FOR HUMAN COGNITIVE AND BRAIN SCIENCES · Dec 10, 2024
Trial Information
Current as of July 21, 2025
Completed
Keywords
ClinConnect Summary
Aims of the present research project are to assess the effect of dopaminergic modulation on BCI performance in healthy elderly subjects to understand the underlying neurophysiological mechanisms. The perspective lies in the application of this approach for improved motor recovery after stroke.
Stroke is one of the most common causes of motor function impairment, and its prevalence is expected to rise due to an aging population. Stroke survivors often experience some level of spontaneous recovery of motor function during the acute stage and reach a functional plateau after which the recover...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age: between 18 and 80 years old at the time of signing the consent form
- • BCI naïve
- • MRI compatible
- • Participation in a detailed discussion on the explanation of the experiment
- • Signing of consent to participate in each experiment
- Exclusion Criteria:
- • Sensory deficits (visual and auditory)
- • Wernicke's or global aphasia
- • Strong spasticity
- • Neurological and/or psychiatric diseases
- • Severe pre-existing lung or heart diseases; Gastrointestinal diseases; Malignant disease
- • Thyroid diseases
- • Taking other medications
- • Narrow angle glaucoma
- • Non-age-related otological diseases
- • Stimulators (cardiac, neuro, etc.)
- • Participation in a similar study
- • Fractures or lesions in the upper extremities
- • Preceding neurosurgical procedures
- • Inability to perform the experimental tasks
- • Inability to give consent
- • Have contraindication for magnetic resonance tomography (MRI) (e.g. braces, cardiac pacemakers, metallic implants that might interfere with the MR signal, claustrophobia)
- • Severe attention and drive disorders
- • Alcohol or drug abuse
- • Pregnancy
- • Women in breastfeeding period
About Max Planck Institute For Human Cognitive And Brain Sciences
The Max Planck Institute for Human Cognitive and Brain Sciences is a leading research institution dedicated to advancing our understanding of cognitive processes and brain function. Located in Leipzig, Germany, the institute conducts cutting-edge research that integrates various disciplines, including psychology, neuroscience, and computational modeling. With a focus on both basic and applied research, the institute aims to uncover the neural mechanisms underlying human cognition and behavior, contributing valuable insights to the fields of psychology, medicine, and artificial intelligence. Its state-of-the-art facilities and collaborative approach position the institute at the forefront of scientific innovation and knowledge dissemination in cognitive neuroscience.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Leipzig, , Germany
Patients applied
Trial Officials
Arno Villringer, PhD
Study Director
Max Planck Institute for Human Cognitive and Brain Sciences
Bernhard Sehm, PhD
Principal Investigator
Max Planck Institute for Human Cognitive and Brain Sciences
Khosrov A. Grigoryan, MSc
Study Chair
Max Planck Institute for Human Cognitive and Brain Sciences
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported