Ultrasound-guided Thermal Ablation for Benign Thyroid Nodules

Launched by CHINESE PLA GENERAL HOSPITAL · Dec 7, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a treatment called ultrasound-guided thermal ablation for people with benign thyroid nodules, which are non-cancerous lumps in the thyroid gland. The goal is to see how effective this treatment is over the long term, especially for those who have concerns about their nodules causing cosmetic or symptom issues, or who may not be eligible or willing to have surgery.

To participate in this trial, individuals need to have confirmation from two separate tests that their nodules are benign, and they should not show any signs of cancer on ultrasound. Participants must also be at least 65 years old and have a follow-up period of at least 12 months. Throughout the trial, participants can expect regular check-ups to monitor their condition and see how well the treatment works. This trial is currently recruiting participants of all genders who meet the eligibility criteria.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. confirmation of benign nodule status on two separate fine- needle aspiration or core-needle biopsy
• • 2. no suspicious malignant features on ultrasound examination
• • 3. report of cosmetic and/ or symptomatic problems or concern of nodules growing rapidly or malignant transformation
• • 4. refusal or ineligibility for surgery
• • 5. follow-up time ≥12 months
• Exclusion Criteria:
• • 1. follicular neoplasm or malignancy findings on biopsy
• • 2. nodules with benign result on biopsy had suspicious of malignancy in US
• • 3. patients with contra-lateral vocal cord paralysis
• • 4. previous radiation to the head and neck
• • 5. follow- up time less than 12 months