Exploring Neurophysiological Markers of Brain Health

Launched by THE UNIVERSITY OF TEXAS AT DALLAS · Dec 9, 2024

Keywords

ClinConnect Summary

This clinical trial, titled "Exploring Neurophysiological Markers of Brain Health," is looking at how brain imaging techniques can help us understand brain health better. The researchers will use a method called transcranial magnetic stimulation (TMS) along with electroencephalography (EEG), which are non-invasive ways to study the brain. They are particularly interested in finding out more about how our brain functions in relation to healthy lifestyle choices and behaviors.

To be eligible for this study, participants should be at least 22 years old, fluent in English, and currently involved in The BrainHealth Project. They should also meet safety requirements for brain imaging, which means they need to have no significant medical issues that could interfere with the tests. Participants will undergo brain imaging and might also be asked about their behaviors and lifestyle. It’s a great opportunity to contribute to research that could help improve our understanding of brain health!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Must be an active brain imaging participant in The BrainHealth Project (NCT04869111)
• • Minimum age of 22
• • Fluent in English
• • Able to read \& hear information over a computer
• • Must pass an MRI safety screener to assess the presence of contraindicators for MRI compatibility (i.e., non-removable metal within/on the body, claustrophobia, pregnancy, non-correctable vision problems, head trauma, and CNS disease)or other standard requirements as determined by the Imaging Center.
• • Must pass a modified TMS Adult Safety Screen
• • Meet all criteria for study as determined by the study physician
• Exclusion Criteria:
• • A diagnosis of a neurodegenerative disease
• • A history of stroke, concussion, or brain injury that currently hinders them from functioning at their prior level
• • A diagnosis of autism spectrum disorder that currently hinders them from functioning independently.
• • Metallic brain implants or fragments (like a shunt, pacemaker, clips, coils, bullet fragments, cochlear implants)
• • Magnetically activated implants or electronically implanted devices
• • Medication pumps
• • Personal or family history of epilepsy, seizure(s), seizure disorder.
• • History of, or risk factors for syncope (fainting)
• • Report significant cognitive challenges
• • Report untreated health issues (like substance abuse, hypertension, hypo- or hyper-thyroidism)
• • Have claustrophobia