The Planetary Outcomes After Intracranial Haemorrhage Study

Launched by UNIVERSITY OF CAMBRIDGE · Dec 9, 2024

Keywords

ClinConnect Summary

The Planetary Outcomes After Intracranial Haemorrhage Study is a clinical trial aimed at understanding how patients with severe strokes, caused by bleeding in the brain (known as intracranial haemorrhage), are treated around the world. Every year, millions of people suffer from strokes, especially in low- and middle-income countries where healthcare resources may be limited. This study will gather important information on patients of all ages who are hospitalized for this type of stroke, tracking their care from the moment they arrive at the hospital until they are discharged or for up to 30 days. By observing how patients are managed, the researchers hope to identify areas where care can be improved, ultimately aiming to enhance survival rates and outcomes for these patients.

To be eligible for this study, participants must be of any age and diagnosed with spontaneous intracranial haemorrhage, meaning the bleeding happened without any prior injury. They must also be admitted to the hospital for treatment, whether that involves observation or more intensive procedures. Notably, the study will not include patients whose bleeding is caused by trauma or certain medical procedures. While participants won’t receive any direct changes to their treatment as part of the study, their experiences will provide valuable insights into the healthcare challenges faced by patients with this serious condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients of any age with the presence of spontaneous intracranial haemorrhage (parenchymal, intraventricular and / or subarachnoid haemorrhage) on intracranial imaging (and absence of a history of trauma).
• AND:
• • • Admission to hospital for sICH management. This includes admission for observation, conservative or interventional management to both ward-based and critical care settings.
• Exclusion Criteria:
• • Patients who have a clear history of trauma as the primary cause of the haemorrhage and therefore are diagnosed with traumatic intracranial haemorrhage.
• • Patients with subdural or extradural haematomas but no clear history of trauma.
• • Patients with intracranial haemorrhage occurring as a complication of a procedure or intervention (e.g. post-operative haematoma) or iatrogenic (e.g. after thrombolysis for ischaemic stroke).
• • Patients who undergo elective (planned admission to hospital) or semi-elective (where a patient was initially admitted to hospital, then discharged from hospital and re-admitted for surgery) procedures.
• • Patients re-admitted to hospital within 30 days of the initial admission with sICH (including those re-admitted for acute management of sICH-related complications).
• • Patient presenting to the emergency department (ED) but discharged home from the ED immediately without a period of observation or admission to a ward.