Ultrasound-guided Thermal Ablation for Papillary Thyroid Carcinoma

Launched by CHINESE PLA GENERAL HOSPITAL · Dec 12, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a treatment called ultrasound-guided thermal ablation for patients with papillary thyroid carcinoma, which is a type of thyroid cancer. The goal is to see how well this treatment works over the long term. The trial is currently looking for participants aged between 18 and 80 who have been diagnosed with papillary thyroid cancer that is 2.0 cm or smaller and has not spread beyond the thyroid gland.

If you decide to participate, you can expect to undergo the thermal ablation treatment, which uses ultrasound to guide the procedure, and then you'll be monitored for at least a year to track your health and any changes in the cancer. It’s important to know that this study is not for everyone; for instance, individuals with more aggressive forms of thyroid cancer, those who have received radiation to the neck, or those with certain health issues may not qualify. This trial provides a unique opportunity to explore a new approach to treating thyroid cancer while contributing to medical research.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. patients age between 18 and 80 year old, both sex
• • 2. papillary thyroid carcinoma confirmed by core-needle biopsy or fine-needle aspiration
• • 3. the largest diameter ≤2.0 cm
• • 4. no clinical or imaging evidences of extrathyroidal extension, lymph node metastasis and distant metastasis on ultrasound, neck and chest CT
• • 5. follow-up period ≥12 months
• Exclusion Criteria:
• • 1. patients with convincing evidence of aggressive papillary thyroid carcinoma or other type of thyroid cancer by biopsy
• • 2. history of neck radiation
• • 3. coagulation disorder, serious heart, respiratory, liver, or renal failure
• • 4. dysfunction of the vocal cord on the opposite side